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Home > Products >  Aprotinin

Aprotinin CAS NO.9087-70-1

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  • Product Details

Keywords

  • trypsin inhibitor
  • BPTI
  • high purity

Quick Details

  • ProName: Aprotinin
  • CasNo: 9087-70-1
  • Application: trypsin inhibitor
  • ProductionCapacity: Metric Ton/Day
  • Purity: high purity
  • LimitNum: 0 Metric Ton

Superiority

Source

E. Coli

Purified by

HPLC

Format

Liquid

Specific activity

≥ 3.0 EPU/mg pro.

Purity

≥ 95% 

 

Details

Recombinant Aprotinin

Catalog Number: RTI16

Anonym: Trypsin Inhibitor

CAS: 9087-70-1

Source: Expressed in E. Coli

 

DESCRIPTION

Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes and dissociating at pH >10.0 or <3.0. Effective concentration is equimolar with protease.

 

RECOMBINANT, ANIMAL COMPONENTS FREE

Recombinant aprotinin is expressed in E. Coli, and purified by HPLC. It contains no animal-derived components. This is a recombinant form of bovine lung aprotinin, which is traditionally isolated from bovine lung by methods involving fractional precipitation, gel filtration, and ion exchange chromatography.

 

MAIN FEATURES

Source

E. Coli

Purified by

HPLC

Format

Liquid

Specific activity

≥ 3.0 EPU/mg pro.

Purity

≥ 95%

UNIT DEFINITION:One trypsin inhibitor unit (EPU) will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1.0 μmol of N-benzoyl-L-arginineethyl ether(BAEE) per sec at pH 7.6 at 25 °C.

A conversion factor for Aprotinin is: 1 EPU= 1 USP Aprotinin Unit = 1800 KIU.

 

STORAGE INSTRUCTIONS

Recombinant aprotinin should be stored under -20°C or below in sealed container.It is stable within 24 months.

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